Chromosome-segment scanning for gain- or loss-of-function screening (CHASING)

Summary: Identifying beneficial or functional mutations for a specific species is a task always relies on the labor-intensive construction of a library containing thousands of single-gene knockout or interference strains. Here, we systematically demonstrated that the task could be done by constructi...

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Bibliographic Details
Main Authors: Yan Xia, Lichao Sun, Zeyu Liang, Zhongrao Han, Jing Li, Pengyu Dong, Yi-Xin Huo, Shuyuan Guo
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S258900422500745X
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