Immunotherapy: An Optimal Control Theory Approach
We investigate mathematical models for the dynamics between tumor cells, immune-effector cells, and cytokine interleukin-2 (IL-2). To better determine under what circumstances the tumor can be eliminated, we implement optimal control theory. We design two control functionals, the first functional ha...
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Main Authors: | K. Renee Fister, Jennifer Hughes Donnelly |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2005-07-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.499 |
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