Self-assembled latanoprost loaded soluplus nanomicelles as an ophthalmic drug delivery system for the management of glaucoma

Self-assembled latanoprost loaded soluplus nanomicelles as an ophthalmic drug delivery system for the management of glaucoma

Abstract Glaucoma, a leading cause of blindness due to elevated intraocular pressure (IOP), is managed with medications like latanoprost (LAT), a prostaglandin analogue, to enhance aqueous outflow. Despite the challenge posed by eye anatomy and tear dynamics, effective ocular bioavailability via top...

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Bibliographic Details
Main Authors: Shazma Gohar, Zafar Iqbal, Fazli Nasir, Muzna Ali Khattak, Gul e Maryam, Sadia Pervez, Fawaz Alasmari, Steven H. Neau, Syeda Rabqa Zainab, Arbab Tahir Ali, Altaf ur Rahman
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Intraocular pressure
Occular drug delivery
BCS class II drug
Nanomicelles
Soluplus
Particle size distribution
Online Access:https://doi.org/10.1038/s41598-024-78244-2
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https://doi.org/10.1038/s41598-024-78244-2

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