Fast and efficient method for parallel construction of targeted exome and methylome single-stranded DNA sequencing libraries

Abstract Based on single-stranded DNA library method, we established an efficient workflow to parallelly construct targeted genomic and epigenomic sequencing libraries from a small amount of DNA. We applied the protocol to nine pediatric brain cancer DNA samples containing various extents of damage...

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Bibliographic Details
Main Authors: Eunhye Kim, Sinae An, Heerak Ahn, Junghyun Lim, Seung‑Ki Kim, Ae Kyung Park
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-91537-4
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