Deciphering the mechanistic roles of ADARs in cancer pathogenesis, tumor immune evasion, and drug resistance

RNA is a fundamental biological macromolecule that undergoes several post-transcriptional modifications, including adenosine to inosine (A-to-I) editing by adenosine deaminases acting on RNA (ADARs). These essential enzymes catalyze the conversion of A-to-I in double-stranded RNA (dsRNA) molecules,...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaoke Wang, Fei Yin, Yangfang He, Yue Qiao, Yan Yan, Jingru Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1621585/full
Tags: Add Tag
No Tags, Be the first to tag this record!