QSAR, Molecular Docking, and Pharmacokinetic Studies of 1,8-Naphthyridine Derivatives as Potential Anticancer Agents Targeting DNA Topoisomerase II
This study aimed to design novel 1,8-naphthyridine derivatives as potential anticancer agents that target topoisomerase II via a ligand-based drug design strategy. We developed a robust quantitative structure–activity relationship model via multiple linear regression, achieving a coefficient of dete...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Association for the Advancement of Science (AAAS)
2025-01-01
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| Series: | Journal of Bio-X Research |
| Online Access: | https://spj.science.org/doi/10.34133/jbioxresearch.0047 |
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