Changes in L‐phenylalanine concentration reflect and predict response to anti‐PD‐1 treatment combined with chemotherapy in patients with non‐small cell lung cancer

Changes in L‐phenylalanine concentration reflect and predict response to anti‐PD‐1 treatment combined with chemotherapy in patients with non‐small cell lung cancer

Abstract Chemotherapy combined with checkpoint blockade antibodies targeting programmed cell death protein (PD‐1) has achieved remarkable success in non‐small cell lung cancer. However, few patients benefit from long‐term treatment. Therefore, biomarkers capable of guiding the optimal therapeutic se...

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Bibliographic Details
Main Authors: Yaqing Liu, Yu Ping, Liubo Zhang, Qitai Zhao, Yachang Huo, Congcong Li, Jiqi Shan, Yanwen Qi, Liping Wang, Yi Zhang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:MedComm
Subjects:
immunotherapy
non‐targeted metabolomics
NSCLC
serum metabolomics
Online Access:https://doi.org/10.1002/mco2.70100
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https://doi.org/10.1002/mco2.70100

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