Maximum likelihood inference for multivariate delay differential equation models

Maximum likelihood inference for multivariate delay differential equation models

Abstract The maximum likelihood inference framework for delay differential equation models in the multivariate settings is developed. The number of delay parameters is assumed to be one or more. This study does not make any restrictive assumptions on the form of the underlying delay differential equ...

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Bibliographic Details
Main Authors: Ahmed Adly Mahmoud, Abdalla Rabie, Sarat Chandra Dass, Ohud A. Alqasem, Getachew Tekle Mekiso, Eslam Hussam, Ahmed M. Gemeay
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Delay differential equation (DDE)
Delay differential equation models (DDEMs)
Delayed pharmacokinetic models
Delayed susceptible-infective-recovered (SIR) model
Maximum likelihood estimation (MLE)
Online Access:https://doi.org/10.1038/s41598-025-07227-8
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https://doi.org/10.1038/s41598-025-07227-8

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