Glibenclamide Administration Attenuates Infarct Volume, Hemispheric Swelling, and Functional Impairments following Permanent Focal Cerebral Ischemia in Rats

Studies from a single laboratory have shown that in rodent models of permanent stroke, administration of the sulfonylurea glibenclamide (Glib) is highly effective in reducing edema, mortality, and lesion volume. The Stroke Therapy Academic Industry Roundtable (STAIR) recommends that new acute treat...

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Bibliographic Details
Main Authors: Bushra Wali, Tauheed Ishrat, Fahim Atif, Fang Hua, Donald G. Stein, Iqbal Sayeed
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Stroke Research and Treatment
Online Access:http://dx.doi.org/10.1155/2012/460909
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