The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans.

During normal development or during disease, animal cells experience hypoxic (low oxygen) conditions, and the hypoxia-inducible factor (HIF) transcription factors implement most of the critical changes in gene expression that enable animals to adapt to this stress. Here, we examine the roles of HIF-...

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Bibliographic Details
Main Authors: Yi Zhang, Zhiyong Shao, Zhiwei Zhai, Chuan Shen, Jo Anne Powell-Coffman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006348&type=printable
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