Cannabidiol potentiates p53-driven autophagic cell death in non-small cell lung cancer following DNA damage: a novel synergistic approach beyond canonical pathways

Cannabidiol potentiates p53-driven autophagic cell death in non-small cell lung cancer following DNA damage: a novel synergistic approach beyond canonical pathways

Abstract The search for more effective and safer cancer therapies has led to an increasing interest in combination treatments that use well-established agents. Here we explore the potential of cannabidiol (CBD), a compound derived from cannabis, to enhance the anticancer effects of etoposide in non-...

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Main Authors: Youngsic Jeon, Taejung Kim, Hyukjoon Kwon, Young Nyun Park, Tae-Hyung Kwon, Min Hong, Kyung-Chul Choi, Jungyeob Ham, Young-Joo Kim
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01444-x
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https://doi.org/10.1038/s12276-025-01444-x

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