Effect of urea and squaramide IMPDH inhibitors on C. parvum: in vitro trial design impacts the assessment of drug efficacy

The protozoan parasite Cryptosporidium is the etiological agent of cryptosporidiosis, a ubiquitous diarrheic disease affecting humans and animals. Treatment options are limited, highlighting an urgent need for novel therapeutics. Despite decades of research and a wide diversity of strategies to tack...

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Bibliographic Details
Main Authors: Anne-Charlotte Lenière, Amit Upadhyay, Jérôme Follet, Timothy P. O'Sullivan
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211320725000156
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