Deciphering the tumor-suppressive role of RBMS3 in lung adenocarcinoma through genomic insights into prognosis and mechanisms

Deciphering the tumor-suppressive role of RBMS3 in lung adenocarcinoma through genomic insights into prognosis and mechanisms

Abstract Lung adenocarcinoma (LUAD) is a leading cause of cancer-related mortality, underscoring the urgent need for novel biomarkers and therapeutic targets. Through transcriptomic analysis of 4456 genes in TCGA-LUAD cohorts, we identified RBMS3 as a significantly downregulated tumor suppressor (lo...

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Bibliographic Details
Main Authors: Li Lv, Tengxiang Zhong, Zhenkun Li, Wenhui Zhang, Yi Zhang, Ying Liang, Rongqing Li, Mingxia Ding, Jie Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Lung adenocarcinoma
RBMS3
Prognosis
Differentially expressed genes
Risk score model
Online Access:https://doi.org/10.1038/s41598-025-95432-w
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https://doi.org/10.1038/s41598-025-95432-w

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