Optimization of fermentation conditions to increase the production of antifungal metabolites from Streptomyces sp. KN37

Optimization of fermentation conditions to increase the production of antifungal metabolites from Streptomyces sp. KN37

Abstract The bacterium Streptomyces sp. KN37 was isolated from the soil of Kanas, Xinjiang. The broth dilution of strain KN37 has a strong inhibitory effect against a variety of crop pathogenic fungi. However, in practical applications, its effective biological activity is limited by medium formulat...

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Bibliographic Details
Main Authors: Xiaoyue Yang, Lijing Yuan, Muhammad Zeeshan, Chuntian Yang, Wen Gao, Guoqiang Zhang, Chunjuan Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Microbial Cell Factories
Subjects:
Streptomyces sp. KN37
Fermentation condition optimization
Plackett-burman design
Central composite design
Online Access:https://doi.org/10.1186/s12934-025-02652-w
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