Adverse events in the nervous system associated with blinatumomab: a real-world study

Adverse events in the nervous system associated with blinatumomab: a real-world study

Abstract Background Nervous system toxicity (NST) is a frequent and serious adverse event (AE) associated with blinatumomab, the first bispecific antibody drug targeting CD19 and CD3. Real-world data are needed to better understand the incidence and characteristics of NST in clinical practice. Metho...

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Main Authors: Wen Gao, Jingwei Yu, Yifei Sun, Zheng Song, Xia Liu, Xue Han, Lanfan Li, Lihua Qiu, Shiyong Zhou, Zhengzi Qian, Xianhuo Wang, Huilai Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Medicine
Subjects:
Blinatumomab
Nervous system toxicity
Pharmacovigilance
FDA Adverse Event Reporting System (FAERS)
Online Access:https://doi.org/10.1186/s12916-025-03913-6
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https://doi.org/10.1186/s12916-025-03913-6

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