Efficacy, safety, and therapeutic drug monitoring of polymyxin B sulfate and colistin sulfate in critically ill patients: a real-world retrospective study

Efficacy, safety, and therapeutic drug monitoring of polymyxin B sulfate and colistin sulfate in critically ill patients: a real-world retrospective study

BackgroundPolymyxin B sulfate (PBS) and colistin sulfate (CS) are the last-line treatments for infections caused by multidrug-resistant Gram-negative bacteria, but their efficacy and safety have not been validated. The aims of the current study were to (1) determine their efficacy and safety among c...

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Bibliographic Details
Main Authors: Yijing Zhang, Chuhui Wang, Jiaojiao Chen, Chuqi Bai, Dan Sun, Yulan Qiu, Mengmeng Teng, Yalin Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
polymyxin B
colistin sulfate
critically ill patients
multidrug-resistant Gram-negative bacteria
therapeutic drug monitoring
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1466888/full
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