Microbial Influences on Amyotrophic Lateral Sclerosis: The Gut–Brain Axis and Therapeutic Potential of Microbiota Modulation

Microbial Influences on Amyotrophic Lateral Sclerosis: The Gut–Brain Axis and Therapeutic Potential of Microbiota Modulation

Background/Objectives: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the progressive degeneration of motor neurons. The gut microbiota, a community of microorganisms in the digestive tract, has recently been implicated in ALS pathogenesis through its influence...

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Main Authors: Victòria Ayala, Laia Fontdevila, Santiago Rico-Rios, Mònica Povedano, Pol Andrés-Benito, Pascual Torres, José C. E. Serrano, Reinald Pamplona, Manuel Portero-Otin
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Sclerosis
Subjects:
probiotics
motor neuron disease
dysbiosis
neuroinflammation
heterogeneity
gut–brain axis
Online Access:https://www.mdpi.com/2813-3064/3/1/8
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