Mechanism of Astragaloside-Brucea javanica oil nanoemulsion against oral squamous cell carcinoma through CDK1/MTFR2: Network pharmacology, bioinformatics, and experimental studies.

Mechanism of Astragaloside-Brucea javanica oil nanoemulsion against oral squamous cell carcinoma through CDK1/MTFR2: Network pharmacology, bioinformatics, and experimental studies.

<h4>Objective</h4>This study aims to investigate the core target of Astragaloside-Brucea javanica oil nanoemulsion (AS/BJO-NEs) against oral squamous cell carcinoma (OSCC) through network pharmacology, bioinformatics, and in vivo/in vitro experiments, elucidating its effects on epithelia...

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Main Authors: Yihan Lai, Runqiang Liu, Huajie Shao, Juan Zhan, Yujie Ma, Lanfei Zhou, Zhichao Wan, Sicheng Li, Wei Wang, Lin Jiang, Yisen Shao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0329622
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https://doi.org/10.1371/journal.pone.0329622

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