The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations.

The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations.

Rhinovirus infections are the major cause of asthma exacerbations. We hypothesised that IL-15, a cytokine implicated in innate and acquired antiviral immunity, may be deficient in asthma and important in the pathogenesis of asthma exacerbations. We investigated regulation of IL-15 induction by rhino...

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Main Authors: Vasile Laza-Stanca, Simon D Message, Michael R Edwards, Hayley L Parker, Mihnea T Zdrenghea, Tatiana Kebadze, Onn M Kon, Patrick Mallia, Luminita A Stanciu, Sebastian L Johnston
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002114&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002114&type=printable

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