A First-Order Derivative Spectrophotometric Method for the Quantification of Saquinavir in the Presence of Piperine in a Eutectic Mixture

A First-Order Derivative Spectrophotometric Method for the Quantification of Saquinavir in the Presence of Piperine in a Eutectic Mixture

Saquinavir is a drug used as an HIV treatment, with recent reports of new uses. It has poor aqueous solubility and very low oral bioavailability. However, when prepared in a eutectic mixture with the natural bioenhancer, piperine, it demonstrated improvements in these drawbacks. Therefore, consideri...

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Bibliographic Details
Main Authors: Tamara Quesada-Soto, Luis Felipe Vargas-Huertas, José Roberto Vega-Baudrit, Mirtha Navarro-Hoyos, Andrea Mariela Araya-Sibaja
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Analytica
Subjects:
saquinavir
piperine
derivative spectrophotometry
method development
validation
Online Access:https://www.mdpi.com/2673-4532/5/4/42
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