Pharmacogenomics-Based Detection of Variants Involved in Pain, Anti-inflammatory and Immunomodulating Agents Pathways by Whole Exome Sequencing and Deep in Silico Investigations Revealed Novel Chemical Carcinogenesis and Cancer Risks

Background: Next-Generation Sequencing (NGS) methods specifically Whole-Exome Sequencing (WES) have demonstrated promising findings with a high accuracy of 91%-99% in Pharmacogenomics (PGx). A PGx-based panel can be utilized to minimize adverse drug reactions (ADRs) and maximize the treatment effica...

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Bibliographic Details
Main Authors: Alireza Sharafshah, Majid Motovali-Bashi, Parvaneh Keshavarz
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2025-02-01
Series:Iranian Journal of Medical Sciences
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Online Access:https://ijms.sums.ac.ir/article_50438_08d496e83abcf5314728148bca1bcbab.pdf
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