Schwann cells modified to secrete MANF is a potential cellular therapy for peripheral nerve regeneration

Schwann cells modified to secrete MANF is a potential cellular therapy for peripheral nerve regeneration

Abstract Effective therapies for peripheral nerve repair are still lacking despite active research in this field over the past years. The limited knowledge of biomolecules that equally promote axon regeneration and glial cell dynamics, which are critical for nerve regeneration, poses a major challen...

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Bibliographic Details
Main Authors: Bhadrapriya Sivakumar, Caleb Hammond, Valeria Martinez, Nickson Joseph, Johnson V. John, Anil Kumar, Anand Krishnan
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:Cell Regeneration
Subjects:
MANF
Nerve regeneration
Schwann cell
Sensory neuron
Neurite outgrowth
Dorsal root ganglia
Online Access:https://doi.org/10.1186/s13619-025-00247-9
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https://doi.org/10.1186/s13619-025-00247-9

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