Fatty acids as potential biomarkers of stearoyl-CoA desaturase inhibition: Variation in healthy subjects and Parkinson's disease patients

Fatty acids as potential biomarkers of stearoyl-CoA desaturase inhibition: Variation in healthy subjects and Parkinson's disease patients

This study aimed to assess the naturally occurring variation in plasma fatty acids in healthy subjects and Parkinson’s disease (PD) patients. Alpha-synuclein (aSyn) plays a major role in Parkinson’s disease. Inhibition of stearoyl-CoA desaturase (SCD) reduces levels of mono-unsaturated C16 and C18 f...

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Bibliographic Details
Main Authors: Pepijn P.N.M. Eijsvogel, Andriy A. Gorbenko, Dan F. Tardiff, Michelle Skupien, Ken Rhodes, Robert H. Scannevin, Yalcin Yavuz, Emilie M.J. van Brummelen, Brigitte Robertson, Philip H.C. Kremer, Geert Jan Groeneveld
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Biomarkers in Neuropsychiatry
Subjects:
Parkinson disease
Stearoyl-CoA desaturase
Fatty acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2666144625000140
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http://www.sciencedirect.com/science/article/pii/S2666144625000140

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