Comprehensive molecular analysis of 26 newly established human pancreatic ductal adenocarcinoma cell lines reveals two clusters with variating drug sensitivities

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a malignant form of cancer with the worst survival rate and an extremely low rate of response to treatments. The development and molecular characterization of pancreatic cancer cell lines (PCCLs) are essential for studying the biology of...

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Bibliographic Details
Main Authors: Ju Eun Maeng, Jae-Hyeon Kim, Soon-Chan Kim, Won-Gun Yun, Wooil Kwon, Youngmin Han, Do-Youn Oh, Sang Hyub Lee, Jin-Young Jang, Ja-Lok Ku
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cancer Cell International
Online Access:https://doi.org/10.1186/s12935-025-03671-8
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