Pectin-Zein-IPA nanoparticles promote functional recovery and alleviate neuroinflammation after spinal cord injury

Pectin-Zein-IPA nanoparticles promote functional recovery and alleviate neuroinflammation after spinal cord injury

Abstract Introduction Spinal cord injury (SCI) impairs the balance of gut microbiomes, which further aggravates inflammation in the injured areas and inhibits axonal regeneration. The intestinal microbiome plays an important role in SCI and regulating intestinal microbiome promotes SCI repair. Howev...

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Main Authors: Xianghang Chen, Beini Wang, Abdullah Al Mamun, Kaiyi Du, Shengfu Wang, Qianqian Hu, Xinyuan Chen, Yang Lu, Anyu Du, Yueqi Wu, Jiaqin Shao, Shuangshuang Wang, Chang Jiang, Kailiang Zhou, Siwang Hu, Jian Xiao
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Nanobiotechnology
Subjects:
Spinal cord injury
Indole-3 propionate
Pectin
Zein
Microbiome metabolite
Online Access:https://doi.org/10.1186/s12951-025-03224-1
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https://doi.org/10.1186/s12951-025-03224-1

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