Patient-derived response estimates from zero-passage organoids of luminal breast cancer

Abstract Background Primary luminal breast cancer cells lose their identity rapidly in standard tissue culture, which is problematic for testing hormone interventions and molecular pathways specific to the luminal subtype. Breast cancer organoids are thought to retain tumor characteristics better, b...

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Bibliographic Details
Main Authors: Róża K. Przanowska, Najwa Labban, Piotr Przanowski, Russell B. Hawes, Kristen A. Atkins, Shayna L. Showalter, Kevin A. Janes
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Breast Cancer Research
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Online Access:https://doi.org/10.1186/s13058-024-01931-5
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