Positron Emission Tomographic Imaging of Iodine 124 Anti–Prostate Stem Cell Antigen–Engineered Antibody Fragments in LAPC-9 Tumor–Bearing Severe Combined Immunodeficiency Mice
The humanized antibody (hu1G8) has been shown to localize to prostate stem cell antigen (PSCA) and image PSCA-positive xenografts. We previously constructed hu1G8 anti-PSCA antibody fragments and tested them for tumor targeting and the ability to image prostate cancer at early and late time points p...
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| Main Authors: | Jeffrey V. Leyton, Tove Olafsen, Eric J.M. Lepin, Scott Hahm, Humphrey Fonge, Robert E. Reiter, Anna M. Wu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2013-05-01
|
| Series: | Molecular Imaging |
| Online Access: | https://doi.org/10.2310/7290.2012.00033 |
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