Positron Emission Tomographic Imaging of Iodine 124 Anti–Prostate Stem Cell Antigen–Engineered Antibody Fragments in LAPC-9 Tumor–Bearing Severe Combined Immunodeficiency Mice

The humanized antibody (hu1G8) has been shown to localize to prostate stem cell antigen (PSCA) and image PSCA-positive xenografts. We previously constructed hu1G8 anti-PSCA antibody fragments and tested them for tumor targeting and the ability to image prostate cancer at early and late time points p...

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Bibliographic Details
Main Authors: Jeffrey V. Leyton, Tove Olafsen, Eric J.M. Lepin, Scott Hahm, Humphrey Fonge, Robert E. Reiter, Anna M. Wu
Format: Article
Language:English
Published: SAGE Publishing 2013-05-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2012.00033
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