A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon

Eosinophilic colitis is an inflammatory condition in which the wall of the colon becomes infiltrated by eosinophils which stain densely pink on microscopy. It is an uncommon clinical entity which has a long list of differential diagnoses. We present a case of a patient whose biopsy at colonoscopy re...

Full description

Saved in:
Bibliographic Details
Main Authors: David Malcolm Milne, Jason Rattan, Alyssa Muddeen, Amrit A. Rambhajan
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2020/5641701
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832561393937678336
author David Malcolm Milne
Jason Rattan
Alyssa Muddeen
Amrit A. Rambhajan
author_facet David Malcolm Milne
Jason Rattan
Alyssa Muddeen
Amrit A. Rambhajan
author_sort David Malcolm Milne
collection DOAJ
description Eosinophilic colitis is an inflammatory condition in which the wall of the colon becomes infiltrated by eosinophils which stain densely pink on microscopy. It is an uncommon clinical entity which has a long list of differential diagnoses. We present a case of a patient whose biopsy at colonoscopy revealed eosinophilic colitis which led to a delay in the diagnosis and subsequent treatment of colon cancer. A 35-year-old male presented with a six-week history of right lower quadrant abdominal pain associated with diarrhoea and weight loss. Colonoscopy showed an inflamed cecum; computed tomography revealed a small ascitic fluid collection in the right iliac fossa. Biopsy showed eosinophilic colitis, and he was treated conservatively with albendazole and mesalamine. The patient failed to improve over the following month with continued weight loss. A repeat CT scan showed a right iliac fossa mass. A right hemicolectomy was performed with histopathology from the specimen showing mucinous adenocarcinoma. Eosinophilic colitis can mask colon cancer and should be considered a diagnosis of exclusion.
format Article
id doaj-art-e927ab7976e54c848ef505b7c1d4b47e
institution Kabale University
issn 2090-6900
2090-6919
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Case Reports in Surgery
spelling doaj-art-e927ab7976e54c848ef505b7c1d4b47e2025-02-03T01:25:19ZengWileyCase Reports in Surgery2090-69002090-69192020-01-01202010.1155/2020/56417015641701A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the ColonDavid Malcolm Milne0Jason Rattan1Alyssa Muddeen2Amrit A. Rambhajan3General Surgery Department, General Hospital Port of Spain, Trinidad and TobagoGeneral Surgery Department, General Hospital Port of Spain, Trinidad and TobagoGeneral Surgery Department, General Hospital Port of Spain, Trinidad and TobagoGeneral Surgery Department, General Hospital Port of Spain, Trinidad and TobagoEosinophilic colitis is an inflammatory condition in which the wall of the colon becomes infiltrated by eosinophils which stain densely pink on microscopy. It is an uncommon clinical entity which has a long list of differential diagnoses. We present a case of a patient whose biopsy at colonoscopy revealed eosinophilic colitis which led to a delay in the diagnosis and subsequent treatment of colon cancer. A 35-year-old male presented with a six-week history of right lower quadrant abdominal pain associated with diarrhoea and weight loss. Colonoscopy showed an inflamed cecum; computed tomography revealed a small ascitic fluid collection in the right iliac fossa. Biopsy showed eosinophilic colitis, and he was treated conservatively with albendazole and mesalamine. The patient failed to improve over the following month with continued weight loss. A repeat CT scan showed a right iliac fossa mass. A right hemicolectomy was performed with histopathology from the specimen showing mucinous adenocarcinoma. Eosinophilic colitis can mask colon cancer and should be considered a diagnosis of exclusion.http://dx.doi.org/10.1155/2020/5641701
spellingShingle David Malcolm Milne
Jason Rattan
Alyssa Muddeen
Amrit A. Rambhajan
A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon
Case Reports in Surgery
title A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon
title_full A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon
title_fullStr A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon
title_full_unstemmed A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon
title_short A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon
title_sort pink herring in the colon a case report of eosinophilic colitis masking invasive adenocarcinoma of the colon
url http://dx.doi.org/10.1155/2020/5641701
work_keys_str_mv AT davidmalcolmmilne apinkherringinthecolonacasereportofeosinophiliccolitismaskinginvasiveadenocarcinomaofthecolon
AT jasonrattan apinkherringinthecolonacasereportofeosinophiliccolitismaskinginvasiveadenocarcinomaofthecolon
AT alyssamuddeen apinkherringinthecolonacasereportofeosinophiliccolitismaskinginvasiveadenocarcinomaofthecolon
AT amritarambhajan apinkherringinthecolonacasereportofeosinophiliccolitismaskinginvasiveadenocarcinomaofthecolon
AT davidmalcolmmilne pinkherringinthecolonacasereportofeosinophiliccolitismaskinginvasiveadenocarcinomaofthecolon
AT jasonrattan pinkherringinthecolonacasereportofeosinophiliccolitismaskinginvasiveadenocarcinomaofthecolon
AT alyssamuddeen pinkherringinthecolonacasereportofeosinophiliccolitismaskinginvasiveadenocarcinomaofthecolon
AT amritarambhajan pinkherringinthecolonacasereportofeosinophiliccolitismaskinginvasiveadenocarcinomaofthecolon