OSI-027 as a Potential Drug Candidate Targeting Upregulated Hub Protein TAF1 in Potential Mechanism of Sinonasal Squamous Cell Carcinoma: Insights from Proteomics and Molecular Docking

OSI-027 as a Potential Drug Candidate Targeting Upregulated Hub Protein TAF1 in Potential Mechanism of Sinonasal Squamous Cell Carcinoma: Insights from Proteomics and Molecular Docking

Sinonasal squamous cell carcinoma (SNSCC) is a rare tumor with high mortality and recurrence rates. However, SNSCC carcinogenesis mechanisms and potential therapeutic drugs have not been fully elucidated. This study investigated the key molecular mechanisms and hub proteins involved in SNSCC carcino...

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Bibliographic Details
Main Authors: Watcharapong Panthong, Chamsai Pientong, Thawaree Nukpook, Chukkris Heawchaiyaphum, Sirinart Aromseree, Tipaya Ekalaksananan
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biology
Subjects:
sinonasal squamous cell carcinoma
proteomic
spliceosome
repurposing drug
OSI-027
Online Access:https://www.mdpi.com/2079-7737/13/12/1089
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https://www.mdpi.com/2079-7737/13/12/1089

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