Coronary Embolism despite CHA₂DS₂-VASc Score of Zero: Should We Reconsider Anticoagulation?

Coronary embolism (CE) is a rare but important cause of acute coronary syndrome. The most common source of emboli is considered to be infective endocarditis and atrial fibrillation. Various studies have estimated the prevalence of coronary embolism; however, diagnosis is challenging. Often, it is di...

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Main Authors: Ammar Ahmed, Andrew Assaf, Aditi Shankar, Marcel Zughaib
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2021/9912245
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author Ammar Ahmed
Andrew Assaf
Aditi Shankar
Marcel Zughaib
author_facet Ammar Ahmed
Andrew Assaf
Aditi Shankar
Marcel Zughaib
author_sort Ammar Ahmed
collection DOAJ
description Coronary embolism (CE) is a rare but important cause of acute coronary syndrome. The most common source of emboli is considered to be infective endocarditis and atrial fibrillation. Various studies have estimated the prevalence of coronary embolism; however, diagnosis is challenging. Often, it is difficult to differentiate. Nonetheless, this is an important step as treating the underlying cause of an embolism is essential to limit recurrence. However, while this condition may have fatal consequences, due to its uncommon occurrence, there is no consensus on diagnosis and management. We present a case of a 53-year-old obese male, with a history of paroxysmal atrial fibrillation not on anticoagulation due to a low CHA2DS2-VASc score, who presented with chest pain associated with lightheadedness. ECG on admission revealed coarse atrial fibrillation, and troponin was gradually elevating on serial lab workup. Coronary angiography revealed a distal left anterior descending artery occlusion with apical wall akinesis without any evidence of atherosclerotic coronary artery disease. A presumptive diagnosis of coronary embolism secondary to paroxysmal atrial fibrillation was made, and the patient was started on anticoagulation despite a low CHA2DS2-VASc score. This case not only highlights coronary embolism but also illustrates that a low CHA2DS2-VASc score does not mean there is no risk of emboli. For such patients, it is important to take clinical reasoning into account along with the CHA2DS2-VASc score to determine the benefit of anticoagulation.
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spelling doaj-art-e8b6998e1d1f454d8fcf1f72224127872025-02-03T01:26:59ZengWileyCase Reports in Cardiology2090-64042090-64122021-01-01202110.1155/2021/99122459912245Coronary Embolism despite CHA₂DS₂-VASc Score of Zero: Should We Reconsider Anticoagulation?Ammar Ahmed0Andrew Assaf1Aditi Shankar2Marcel Zughaib3Department of Internal Medicine, Ascension Providence Hospital, Southfield, MI, USADepartment of Cardiovascular Disease, Ascension Providence Hospital, Southfield, MI, USADepartment of Internal Medicine, Texas Health Presbyterian Dallas, Dallas, TX, USADepartment of Cardiovascular Disease, Ascension Providence Hospital, Southfield, MI, USACoronary embolism (CE) is a rare but important cause of acute coronary syndrome. The most common source of emboli is considered to be infective endocarditis and atrial fibrillation. Various studies have estimated the prevalence of coronary embolism; however, diagnosis is challenging. Often, it is difficult to differentiate. Nonetheless, this is an important step as treating the underlying cause of an embolism is essential to limit recurrence. However, while this condition may have fatal consequences, due to its uncommon occurrence, there is no consensus on diagnosis and management. We present a case of a 53-year-old obese male, with a history of paroxysmal atrial fibrillation not on anticoagulation due to a low CHA2DS2-VASc score, who presented with chest pain associated with lightheadedness. ECG on admission revealed coarse atrial fibrillation, and troponin was gradually elevating on serial lab workup. Coronary angiography revealed a distal left anterior descending artery occlusion with apical wall akinesis without any evidence of atherosclerotic coronary artery disease. A presumptive diagnosis of coronary embolism secondary to paroxysmal atrial fibrillation was made, and the patient was started on anticoagulation despite a low CHA2DS2-VASc score. This case not only highlights coronary embolism but also illustrates that a low CHA2DS2-VASc score does not mean there is no risk of emboli. For such patients, it is important to take clinical reasoning into account along with the CHA2DS2-VASc score to determine the benefit of anticoagulation.http://dx.doi.org/10.1155/2021/9912245
spellingShingle Ammar Ahmed
Andrew Assaf
Aditi Shankar
Marcel Zughaib
Coronary Embolism despite CHA₂DS₂-VASc Score of Zero: Should We Reconsider Anticoagulation?
Case Reports in Cardiology
title Coronary Embolism despite CHA₂DS₂-VASc Score of Zero: Should We Reconsider Anticoagulation?
title_full Coronary Embolism despite CHA₂DS₂-VASc Score of Zero: Should We Reconsider Anticoagulation?
title_fullStr Coronary Embolism despite CHA₂DS₂-VASc Score of Zero: Should We Reconsider Anticoagulation?
title_full_unstemmed Coronary Embolism despite CHA₂DS₂-VASc Score of Zero: Should We Reconsider Anticoagulation?
title_short Coronary Embolism despite CHA₂DS₂-VASc Score of Zero: Should We Reconsider Anticoagulation?
title_sort coronary embolism despite cha₂ds₂ vasc score of zero should we reconsider anticoagulation
url http://dx.doi.org/10.1155/2021/9912245
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AT andrewassaf coronaryembolismdespitecha2ds2vascscoreofzeroshouldwereconsideranticoagulation
AT aditishankar coronaryembolismdespitecha2ds2vascscoreofzeroshouldwereconsideranticoagulation
AT marcelzughaib coronaryembolismdespitecha2ds2vascscoreofzeroshouldwereconsideranticoagulation