The impact of inflammation and iron metabolism on gene expression alterations in ischemic stroke: a bioinformatics approach

The impact of inflammation and iron metabolism on gene expression alterations in ischemic stroke: a bioinformatics approach

Abstract This study explores the differential expression of inflammation and iron metabolism-related genes (IIMRDEGs) in Ischemic Stroke (IS), a major contributor to global morbidity and mortality. Using the Gene Expression Omnibus (GEO) query tool, we integrated gene expression datasets GSE22255 an...

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Bibliographic Details
Main Authors: Shengwu Wang, Xuemei Li, Youcai Bi, Chao Yan, Yunbo Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Ischemic stroke
Differential expression
Inflammation
Iron metabolism
Immune infiltration
Biomarkers
Online Access:https://doi.org/10.1038/s41598-025-00369-9
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