Elevated cerebrospinal fluid levels of SERPIN E1 in participants with lewy body diseases

Elevated cerebrospinal fluid levels of SERPIN E1 in participants with lewy body diseases

Abstract Parkinson’s disease (PD) exhibits substantial phenotypic variability, likely influenced, at least in part, by proteins associated with pathways integral to aging processes. Plasminogen activator inhibitor-1 (SERPIN E1) is known for its association with aging processes and exacerbated α-Synu...

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Main Authors: Milan Zimmermann, Madeleine Fandrich, Meike Jakobi, Benjamin Röben, Isabel Wurster, Stefanie Lerche, Claudia Schulte, Shahrzad Zimmermann, Christian Deuschle, Nicole Schneiderhan-Marra, Thomas O. Joos, Thomas Gasser, Kathrin Brockmann
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-00984-3
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https://doi.org/10.1038/s41531-025-00984-3

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