PFKFB3 downregulation aggravates Angiotensin II-induced podocyte detachment

PFKFB3 downregulation aggravates Angiotensin II-induced podocyte detachment

Podocytes play a critical role in maintaining normal glomerular filtration, and podocyte loss from the glomerular basement membrane (GBM) initiates and worsens chronic kidney disease (CKD). However, the exact mechanism underlying podocyte loss remains unclear. Fructose-2,6-biphosphatase 3 (PFKFB3) i...

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Bibliographic Details
Main Authors: Xiaoxiao Huang, Zhaowei Chen, Zilv Luo, Yiqun Hao, Jun Feng, Zijing Zhu, Xueyan Yang, Zongwei Zhang, Jijia Hu, Wei Liang, Guohua Ding
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Renal Failure
Subjects:
Angiotensin II
podocyte
PFKFB3
adhesion
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2023.2230318
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https://www.tandfonline.com/doi/10.1080/0886022X.2023.2230318

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