Oversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis
Proliferating animal cells maintain a stable size distribution over generations despite fluctuations in cell growth and division size. Previously, we showed that cell size control involves both cell size checkpoints, which delay cell cycle progression in small cells, and size-dependent regulation of...
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Main Authors: | Shixuan Liu, Ceryl Tan, Chloe Melo-Gavin, Miriam B Ginzberg, Ron Blutrich, Nish Patel, Michael Rape, Kevin G Mark, Ran Kafri |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2025-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/75393 |
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