Microbiome gut community structure and functionality are associated with symptom severity in non-responsive celiac disease patients undergoing a gluten-free diet

Microbiome gut community structure and functionality are associated with symptom severity in non-responsive celiac disease patients undergoing a gluten-free diet

ABSTRACT Non-responsive celiac disease (NRCD) challenges clinicians due to persistent symptoms despite a gluten-free diet (GFD). We present a cross-sectional pilot study including 39 NRCD patients to describe the underlying mechanisms contributing to symptom persistence by integrating different leve...

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Main Authors: Laura Judith Marcos-Zambrano, Blanca Lacruz-Pleguezuelos, Elena Aguilar-Aguilar, Helena Marcos-Pasero, Alberto Valdés, Viviana Loria-Kohen, Alejandro Cifuentes, Ana Ramirez de Molina, Alberto Diaz-Ruiz, Vera Pancaldi, Enrique Carrillo de Santa Pau
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mSystems
Subjects:
microbiome
metabolome
celiac disease
gluten-free diet
co-occurrence networks
symptom association
Online Access:https://journals.asm.org/doi/10.1128/msystems.00143-25
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https://journals.asm.org/doi/10.1128/msystems.00143-25

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