Functionalized Polymeric Microneedles for Transdermal Delivery of Ovalbumin Protein Antigen

Functionalized Polymeric Microneedles for Transdermal Delivery of Ovalbumin Protein Antigen

<b>Background/Objectives:</b> Microneedles represent an innovative transdermal drug delivery approach, especially for protein antigens. This study aimed to develop a dual-functional, dissolvable microneedle system loaded with β-glucan and fucoidan in a hyaluronic acid matrix to achieve t...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yi Liu, Feng Tan, Decheng Zhao, Liwen Zhang, Nianni Zhang, Chengwei Bai, Ziyang Guo, Xiongjian Guan, Guanyu Chen
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Pharmaceutics
Subjects:	dissolvable microneedles transdermal drug delivery immunomodulation reactive oxygen species (ROS) regulation β-glucan fucoidan
Online Access:	https://www.mdpi.com/1999-4923/17/6/737
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Recent progress of polymeric microneedle-assisted long-acting transdermal drug delivery
by: Fanda Meng, et al.
Published: (2024-03-01)

Characteristics of Hydrogels as a Coating for Microneedle Transdermal Delivery Systems with Agomelatine
by: Monika Wojtyłko, et al.
Published: (2025-01-01)

MICRONEEDLES AS A WAY TO INCREASE THE TRANSDERMAL INSULIN DELIVERY
by: E. G. Kuznetsova, et al.
Published: (2017-01-01)

Design of scalable manufacturing process for the production of biodegradable polymeric microneedles for protein transdermal drug delivery
by: M. S. Zolotareva, et al.
Published: (2024-09-01)

Enhanced transdermal delivery of lidocaine cream via ultrasound and microneedle rollers
by: Jiaxiao Sun, et al.
Published: (2025-07-01)

What Is the Optimal Geometry of Dissolving Microneedle Arrays? A Literature Review
by: Maira Visscher, et al.
Published: (2025-01-01)

Transdermal microneedle patch for antioxidants release
by: Samuel Mugo, et al.
Published: (2025-03-01)

A Hierarchical Short Microneedle-Cupping Dual-Amplified Patch Enables Accelerated, Uniform, Pain-Free Transdermal Delivery of Extracellular Vesicles
by: Minwoo Song, et al.
Published: (2025-07-01)

Biodegradable polymeric insulin microneedles – a design and materials perspective review
by: Melbha Starlin Chellathurai, et al.
Published: (2024-12-01)

Enhanced transdermal delivery of pioglitazone hydrochloride via conductive hydrogel microneedles combined with iontophoresis
by: Jianling Hu, et al.
Published: (2025-06-01)

Transdermal delivery of timolol maleate using hydrogel microneedles for the treatment of infantile haemangiomas
by: Xiaokun Lin, et al.
Published: (2025-06-01)

High-Precision Transdermal Drug Delivery Device with Piezoelectric Mechanism
by: Shengyu Liu, et al.
Published: (2025-04-01)

A State‐of‐the‐Art Appraisal of Nanomaterials in Microneedles in the Delivery of Therapeutics and Vaccines
by: Bwalya Angel Witika, et al.
Published: (2025-03-01)

Resveratrol-Loaded Dissolving Microneedles: Fabrication and <i>in vitro</i> Evaluation
by: Banghuai Xing, et al.
Published: (2024-12-01)

Development and optimization of the Glabridin-loaded dissolving microneedle for enhanced treatment of keloid
by: Juan Guo, et al.
Published: (2024-12-01)

Formulation approaches and strategies for transdermal delivery of insulin: special emphasis on microneedle-based systems
by: Eileen Hulambukie, et al.
Published: (2025-06-01)

Microneedles at the Forefront of Next Generation Theranostics
by: Chan Wang, et al.
Published: (2025-06-01)

Novel Antigen-Presenting Cell-Targeted Nanoparticles Enhance Split Vaccine Immunity Through Microneedles Inoculation
by: Xiu X, et al.
Published: (2025-04-01)

Advances in clinical applications of microneedle
by: Kequan Chen, et al.
Published: (2025-06-01)

Comparative analysis of pharmacokinetic parameters of transdermal and intramuscular administration of Galavit®
by: E. G. Kuznetsova, et al.
Published: (2021-07-01)

Influence of microemulsion components on transdermal delivery of immunomodulator glucosaminylmuramyl dipeptide
by: E. G. Kuznetsova, et al.
Published: (2020-10-01)

Enhanced Topical Delivery of Methotrexate via Transferosome-Loaded Microneedle Array Patch: Formulation, Optimization, and In Vitro–In Vivo Assessment
by: Snehal Shinde, et al.
Published: (2025-04-01)

A systematic review of microneedles technology in drug delivery through a bibliometric and patent overview
by: Aniello Cammarano, et al.
Published: (2024-12-01)

Beyond the Needle: Innovative Microneedle-Based Transdermal Vaccination
by: Hiep X. Nguyen
Published: (2025-02-01)

The potential of microneedle platforms in addressing pediatric drug delivery challenges: perspectives of healthcare professionals and parents
by: Heba Y. Raslan, et al.
Published: (2025-07-01)

Facile minocycline deployment in gingiva using a dissolvable microneedle patch for the adjunctive treatment of periodontal disease
by: Huimin Li, et al.
Published: (2025-03-01)

Effect of transdermal immunomodulation on liver regeneration
by: E. G. Kuznetsova, et al.
Published: (2022-04-01)

Dual-responsive copper complex delivered by dissolvable microneedle promotes polymicrobial infection eradication and cutaneous wound healing
by: Sumanta Ghosh, et al.
Published: (2025-10-01)

Photothermal‐Responsive Soluble Microneedle Patches for Meibomian Gland Dysfunction Therapy
by: Fei Yu, et al.
Published: (2025-03-01)

Methodology of the Development of a Topical Transdermal Fucoidan Delivery System
by: E. D. Obluchinskaya, et al.
Published: (2023-02-01)

Multifunctional Hydrogel Microneedles (HMNs) in Drug Delivery and Diagnostics
by: Hossein Omidian, et al.
Published: (2025-03-01)

Microneedles integrated with crystallinity control for poorly water-soluble drugs: Enhanced bioavailability and innovative controlled release system
by: Mi Ran Woo, et al.
Published: (2024-11-01)

Fabrication and Ex-vivo Evaluation of Olanzapine Nanoparticles Based Dissolved Microneedle for Transdermal Delivery
by: Abulfadhel jaber neamah AL-shaibani, et al.
Published: (2025-06-01)

Multifunctional astragalus polysaccharide composited microneedle promotes oral ulcers healing by inhibiting ferroptosis via Nrf2/HO-1/SLC7A11 axis
by: Qiang Zhang, et al.
Published: (2025-06-01)

Microneedles as transdermal drug delivery system for enhancing skin disease treatment
by: Chaoxiong Wu, et al.
Published: (2024-12-01)

Advances in microneedle-based drug delivery system for metabolic diseases: structural considerations, design strategies, and future perspectives
by: Yao Li, et al.
Published: (2025-05-01)

Research Progress on Evaluating the Effectiveness and Safety of Transdermal Absorption of Cosmetics
by: Meixuan Wang, et al.
Published: (2024-12-01)

Research progress of dissolving microneedles in the field of component administration of traditional Chinese medicine
by: Yuting Yang, et al.
Published: (2025-08-01)

Wearable Systems of Reconfigurable Microneedle Electrode Array for Subcutaneous Multiplexed Recording of Myoelectric and Electrochemical Signals
by: Zhengjie Liu, et al.
Published: (2025-06-01)

Self-assembled arginine-based eutectogel microneedles as novel transdermal delivery system for pigmentation treatment
by: Hui Ma, et al.
Published: (2025-06-01)