Functionalized Polymeric Microneedles for Transdermal Delivery of Ovalbumin Protein Antigen

Functionalized Polymeric Microneedles for Transdermal Delivery of Ovalbumin Protein Antigen

<b>Background/Objectives:</b> Microneedles represent an innovative transdermal drug delivery approach, especially for protein antigens. This study aimed to develop a dual-functional, dissolvable microneedle system loaded with β-glucan and fucoidan in a hyaluronic acid matrix to achieve t...

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Bibliographic Details
Main Authors: Yi Liu, Feng Tan, Decheng Zhao, Liwen Zhang, Nianni Zhang, Chengwei Bai, Ziyang Guo, Xiongjian Guan, Guanyu Chen
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceutics
Subjects:
dissolvable microneedles
transdermal drug delivery
immunomodulation
reactive oxygen species (ROS) regulation
β-glucan
fucoidan
Online Access:https://www.mdpi.com/1999-4923/17/6/737
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