Joint fusion of sequences and structures of drugs and targets for identifying targets based on intra and inter cross-attention mechanisms

Abstract Background Accurately identifying targets not only guides treatments for diseases with unclear pathogenic mechanisms, but also reduces pharmaceutical costs and accelerates drug development timelines. However, the primary challenge in targets identification currently lies in the low accuracy...

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Bibliographic Details
Main Authors: Xin Zeng, Guang-Peng Su, Wen-Feng Du, Bei Jiang, Yi Li, Zi-Zhong Yang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
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Online Access:https://doi.org/10.1186/s12915-025-02256-1
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