An In Vitro Approach to Prime or Boost Human Antigen-Specific CD8<sup>+</sup> T Cell Responses: Applications to Vaccine Studies

An In Vitro Approach to Prime or Boost Human Antigen-Specific CD8<sup>+</sup> T Cell Responses: Applications to Vaccine Studies

Although vaccine development has primarily focused on inducing neutralizing antibodies, increasing evidence supports an important role of CD8<sup>+</sup> T cell responses in vaccine effectiveness. Routine assays, which are mainly based on antibody titers, may therefore not accurately ref...

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Bibliographic Details
Main Authors: Hoang Oanh Nguyen, Mariela P. Cabral-Piccin, Victor Appay, Laura Papagno
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Vaccines
Subjects:
vaccination
immunomonitoring
T cells
priming
flow cytometry
Online Access:https://www.mdpi.com/2076-393X/13/7/729
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