Histone methylation regulates Hif‐1 signaling cascade in activation of hepatic stellate cells

Liver fibrosis is characterized by deposition of excessive extracellular matrix (ECM). The major source of ECM is activated hepatic stellate cells (HSCs). Previously, we reported that hypoxia‐inducible factor‐1 (Hif‐1) regulates activation of HSCs through autophagy. In current work, human HSC cell l...

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Bibliographic Details
Main Authors: Fei Hong, Lu Wan, Jie Liu, Ke Huang, Zhenmeng Xiao, Yingjing Zhang, Chunwei Shi
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:FEBS Open Bio
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Online Access:https://doi.org/10.1002/2211-5463.12379
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