Efficacy of virtual reality techniques in cardiopulmonary resuscitation training: protocol for a meta-analysis of randomised controlled trials and trial sequential analysis

Introduction Cardiopulmonary resuscitation (CPR) is the most critical procedure in the rescue of patients with sudden cardiac death (SCD). The success rate of CPR remains far below expectations, which made CPR education identified as the top priority for SCD. CPR training using the virtual reality (...

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Main Authors: Jia Wang, Lu Zhang, Guo Chen, Li Du, Jianqiao Zheng, Xiaoqian Deng
Format: Article
Language:English
Published: BMJ Publishing Group 2022-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/2/e058827.full
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author Jia Wang
Lu Zhang
Guo Chen
Li Du
Jianqiao Zheng
Xiaoqian Deng
author_facet Jia Wang
Lu Zhang
Guo Chen
Li Du
Jianqiao Zheng
Xiaoqian Deng
author_sort Jia Wang
collection DOAJ
description Introduction Cardiopulmonary resuscitation (CPR) is the most critical procedure in the rescue of patients with sudden cardiac death (SCD). The success rate of CPR remains far below expectations, which made CPR education identified as the top priority for SCD. CPR training using the virtual reality (VR) technique is a feasible training method, with a wider population and lower cost, but its efficacy remains controversial. Thus, we will perform a protocol for a systematic review and meta-analysis to identify the efficacy of the VR technique on CPR quality.Methods and analysis We will search PubMed, Web of Science, Cochrane Library, Ovid Medline, Embase, China National Knowledge Infrastructure, Chinese BioMedical Literature, Wanfang and VIP databases from inception to November 2021, to identify randomised controlled trials and the first period in randomised cross-over trials assessing the efficacy of VR techniques versus non-VR techniques for adult participants accepting adult CPR training. No language restrictions will be considered. Data synthesis will be performed using RevMan V.5.4 and Stata/MP V.16.0. Outcome measures will be present as relative risk with 95% CIs for dichotomous data and mean difference with 95% CIs for continuous data. The primary outcome will be the CPR quality defined as chest compression rate and depth. Secondary outcomes will be the overall performance of CPR. Heterogeneity will be assessed by the χ2 test and I2 statistic. Data will be synthesised by either fixed-effects or random-effects models according to the I2 value. Trial sequential analysis and modified Jadad Scale will be used to control the risks of random errors and evaluate the evidence quality. Egger’s regression test and funnel plots will be used to assess the publication bias.Ethics and dissemination Ethical approval was not required for this systematic review protocol. The findings will be disseminated through peer-reviewed publications.PROSPERO registration number CRD42021281059.
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spelling doaj-art-e7c03b5ffac1466c8a289c7340c541e72025-02-01T15:40:14ZengBMJ Publishing GroupBMJ Open2044-60552022-02-0112210.1136/bmjopen-2021-058827Efficacy of virtual reality techniques in cardiopulmonary resuscitation training: protocol for a meta-analysis of randomised controlled trials and trial sequential analysisJia Wang0Lu Zhang1Guo Chen2Li Du3Jianqiao Zheng4Xiaoqian Deng5Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China1Shanghai Cell Therapy Group Co. Ltd, Shanghai, ChinaDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDepartment of Research and Education, Tongji University, Shanghai, Shanghai, ChinaDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaIntroduction Cardiopulmonary resuscitation (CPR) is the most critical procedure in the rescue of patients with sudden cardiac death (SCD). The success rate of CPR remains far below expectations, which made CPR education identified as the top priority for SCD. CPR training using the virtual reality (VR) technique is a feasible training method, with a wider population and lower cost, but its efficacy remains controversial. Thus, we will perform a protocol for a systematic review and meta-analysis to identify the efficacy of the VR technique on CPR quality.Methods and analysis We will search PubMed, Web of Science, Cochrane Library, Ovid Medline, Embase, China National Knowledge Infrastructure, Chinese BioMedical Literature, Wanfang and VIP databases from inception to November 2021, to identify randomised controlled trials and the first period in randomised cross-over trials assessing the efficacy of VR techniques versus non-VR techniques for adult participants accepting adult CPR training. No language restrictions will be considered. Data synthesis will be performed using RevMan V.5.4 and Stata/MP V.16.0. Outcome measures will be present as relative risk with 95% CIs for dichotomous data and mean difference with 95% CIs for continuous data. The primary outcome will be the CPR quality defined as chest compression rate and depth. Secondary outcomes will be the overall performance of CPR. Heterogeneity will be assessed by the χ2 test and I2 statistic. Data will be synthesised by either fixed-effects or random-effects models according to the I2 value. Trial sequential analysis and modified Jadad Scale will be used to control the risks of random errors and evaluate the evidence quality. Egger’s regression test and funnel plots will be used to assess the publication bias.Ethics and dissemination Ethical approval was not required for this systematic review protocol. The findings will be disseminated through peer-reviewed publications.PROSPERO registration number CRD42021281059.https://bmjopen.bmj.com/content/12/2/e058827.full
spellingShingle Jia Wang
Lu Zhang
Guo Chen
Li Du
Jianqiao Zheng
Xiaoqian Deng
Efficacy of virtual reality techniques in cardiopulmonary resuscitation training: protocol for a meta-analysis of randomised controlled trials and trial sequential analysis
BMJ Open
title Efficacy of virtual reality techniques in cardiopulmonary resuscitation training: protocol for a meta-analysis of randomised controlled trials and trial sequential analysis
title_full Efficacy of virtual reality techniques in cardiopulmonary resuscitation training: protocol for a meta-analysis of randomised controlled trials and trial sequential analysis
title_fullStr Efficacy of virtual reality techniques in cardiopulmonary resuscitation training: protocol for a meta-analysis of randomised controlled trials and trial sequential analysis
title_full_unstemmed Efficacy of virtual reality techniques in cardiopulmonary resuscitation training: protocol for a meta-analysis of randomised controlled trials and trial sequential analysis
title_short Efficacy of virtual reality techniques in cardiopulmonary resuscitation training: protocol for a meta-analysis of randomised controlled trials and trial sequential analysis
title_sort efficacy of virtual reality techniques in cardiopulmonary resuscitation training protocol for a meta analysis of randomised controlled trials and trial sequential analysis
url https://bmjopen.bmj.com/content/12/2/e058827.full
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