Simultaneous Determination of Cyclosporine A, Tacrolimus, Sirolimus, and Everolimus in Whole-Blood Samples by LC-MS/MS

Simultaneous Determination of Cyclosporine A, Tacrolimus, Sirolimus, and Everolimus in Whole-Blood Samples by LC-MS/MS

Objectives. Cyclosporine A (CyA), tacrolimus (TRL), sirolimus (SIR), and everolimus (RAD) are immunosuppressive drugs frequently used in organ transplantation. Our aim was to confirm a robust sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for determination o...

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Main Authors: Mustafa Karapirli, Murat Kizilgun, Ozgur Yesilyurt, Husamettin Gul, Zeki Ilker Kunak, Emin Ozgur Akgul, Enis Macit, Tuncer Cayci, Yasemin Gulcan Kurt, Ibrahim Aydin, Hakan Yaren, Melik Seyrek, Erdinc Cakir, Halil Yaman
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/571201
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http://dx.doi.org/10.1100/2012/571201

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