IL-37 inhibited inflammation to improve gestational diabetes mellitus through the GSK3/NF-κB pathway

Abstract Purpose To investigate the role of IL-37 in gestational diabetes mellitus (GDM) and its potential mechanisms. Methods A GDM mouse model was constructed with a high-fat diet (HFD). The effects of IL-37 on glucose metabolism, insulin sensitivity, insulin resistance, and placental inflammation...

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Bibliographic Details
Main Authors: Meiyu Song, Guanli Zhang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Online Access:https://doi.org/10.1186/s13098-025-01785-7
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