Strategies to Overcome Antigen Heterogeneity in CAR-T Cell Therapy

Chimeric antigen receptor (CAR) gene-modified T-cell therapy has achieved significant success in the treatment of hematological malignancies. However, this therapy has not yet made breakthroughs in the treatment of solid tumors and still faces issues of resistance and relapse in hematological cancer...

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Bibliographic Details
Main Authors: Bohan Zhang, Jiawen Wu, Hua Jiang, Min Zhou
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/5/320
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