The Potential of Lactic Acid Bacteria and Dairy By-Products in Controlling <i>Campylobacter jejuni</i> in Poultry

<i>Campylobacter jejuni</i> (<i>C. jejuni</i>) is the primary <i>Campylobacter</i> species and a major cause of foodborne illness associated with poultry products. This review focuses on lactic acid bacteria (LAB), especially <i>Lactobacillus</i> speci...

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Main Authors: Naga Pavan Kumar Reddy Jonnagiri, Gintare Zakariene, Naila Nawaz, Ausra Gabinaitiene, Artūras Stimbirys
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/5/996
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author Naga Pavan Kumar Reddy Jonnagiri
Gintare Zakariene
Naila Nawaz
Ausra Gabinaitiene
Artūras Stimbirys
author_facet Naga Pavan Kumar Reddy Jonnagiri
Gintare Zakariene
Naila Nawaz
Ausra Gabinaitiene
Artūras Stimbirys
author_sort Naga Pavan Kumar Reddy Jonnagiri
collection DOAJ
description <i>Campylobacter jejuni</i> (<i>C. jejuni</i>) is the primary <i>Campylobacter</i> species and a major cause of foodborne illness associated with poultry products. This review focuses on lactic acid bacteria (LAB), especially <i>Lactobacillus</i> species, and acid whey as a dairy by-product for <i>C. jejuni</i> control in poultry as a sustainable method. LAB strains <i>L. crispatus</i> exhibit a cecal colonization reduction of >90% by competitive exclusion and bacteriocin activity, while <i>L. johnsonii</i> FI9785 decrease bacterial load 4–5 log<sub>10</sub>. Acid whey, which is abundant in organic acids (e.g., lactic acid) and bioactive peptides (e.g., lactoferrin), reduces <i>C. jejuni</i> viability, decreasing the food product contamination on the carcass for a short time by 40%. LAB antimicrobial function becomes more effective when used with acid whey, although specific farm-related variables require additional optimization. Some of the key strategies include co-encapsulating LAB with acid whey or plant-derived antimicrobials for improving survival, conducting in vivo trials in commercial farm conditions to evaluate scalability, and adding whey into feed (1–2% inclusion) or applying it as a pre-slaughter spray. These strategies enable the antibiotic-free production and circular economy goals through repurposing low-cost acid whey. Future studies should directly compare them with standard antimicrobials to confirm their scalability for poultry safety.
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spelling doaj-art-e780c4724b5e400ea24d769898f4979a2025-08-20T03:14:36ZengMDPI AGMicroorganisms2076-26072025-04-0113599610.3390/microorganisms13050996The Potential of Lactic Acid Bacteria and Dairy By-Products in Controlling <i>Campylobacter jejuni</i> in PoultryNaga Pavan Kumar Reddy Jonnagiri0Gintare Zakariene1Naila Nawaz2Ausra Gabinaitiene3Artūras Stimbirys4Department of Food Safety and Quality, Lithuanian University of Health Sciences, LT-44307 Kaunas, LithuaniaDepartment of Food Safety and Quality, Lithuanian University of Health Sciences, LT-44307 Kaunas, LithuaniaDepartment of Food Safety and Quality, Lithuanian University of Health Sciences, LT-44307 Kaunas, LithuaniaDepartment of Food Safety and Quality, Lithuanian University of Health Sciences, LT-44307 Kaunas, LithuaniaDepartment of Food Safety and Quality, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania<i>Campylobacter jejuni</i> (<i>C. jejuni</i>) is the primary <i>Campylobacter</i> species and a major cause of foodborne illness associated with poultry products. This review focuses on lactic acid bacteria (LAB), especially <i>Lactobacillus</i> species, and acid whey as a dairy by-product for <i>C. jejuni</i> control in poultry as a sustainable method. LAB strains <i>L. crispatus</i> exhibit a cecal colonization reduction of >90% by competitive exclusion and bacteriocin activity, while <i>L. johnsonii</i> FI9785 decrease bacterial load 4–5 log<sub>10</sub>. Acid whey, which is abundant in organic acids (e.g., lactic acid) and bioactive peptides (e.g., lactoferrin), reduces <i>C. jejuni</i> viability, decreasing the food product contamination on the carcass for a short time by 40%. LAB antimicrobial function becomes more effective when used with acid whey, although specific farm-related variables require additional optimization. Some of the key strategies include co-encapsulating LAB with acid whey or plant-derived antimicrobials for improving survival, conducting in vivo trials in commercial farm conditions to evaluate scalability, and adding whey into feed (1–2% inclusion) or applying it as a pre-slaughter spray. These strategies enable the antibiotic-free production and circular economy goals through repurposing low-cost acid whey. Future studies should directly compare them with standard antimicrobials to confirm their scalability for poultry safety.https://www.mdpi.com/2076-2607/13/5/996<i>Campylobacter jejuni</i><i>Lactobacillus</i>feed additivesfood safety
spellingShingle Naga Pavan Kumar Reddy Jonnagiri
Gintare Zakariene
Naila Nawaz
Ausra Gabinaitiene
Artūras Stimbirys
The Potential of Lactic Acid Bacteria and Dairy By-Products in Controlling <i>Campylobacter jejuni</i> in Poultry
Microorganisms
<i>Campylobacter jejuni</i>
<i>Lactobacillus</i>
feed additives
food safety
title The Potential of Lactic Acid Bacteria and Dairy By-Products in Controlling <i>Campylobacter jejuni</i> in Poultry
title_full The Potential of Lactic Acid Bacteria and Dairy By-Products in Controlling <i>Campylobacter jejuni</i> in Poultry
title_fullStr The Potential of Lactic Acid Bacteria and Dairy By-Products in Controlling <i>Campylobacter jejuni</i> in Poultry
title_full_unstemmed The Potential of Lactic Acid Bacteria and Dairy By-Products in Controlling <i>Campylobacter jejuni</i> in Poultry
title_short The Potential of Lactic Acid Bacteria and Dairy By-Products in Controlling <i>Campylobacter jejuni</i> in Poultry
title_sort potential of lactic acid bacteria and dairy by products in controlling i campylobacter jejuni i in poultry
topic <i>Campylobacter jejuni</i>
<i>Lactobacillus</i>
feed additives
food safety
url https://www.mdpi.com/2076-2607/13/5/996
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