Identification and validation of three diagnostic autophagy-related genes associated with advanced plaques and immune cell infiltration in carotid atherosclerosis based on integrated bioinformatics analyses

Identification and validation of three diagnostic autophagy-related genes associated with advanced plaques and immune cell infiltration in carotid atherosclerosis based on integrated bioinformatics analyses

Background Autophagy plays a key role in the development of carotid atherosclerosis (CAS). This study aimed to identify key autophagy-related genes (ATGs) related with CAS using bioinformatics analysis, in vivo AS mouse model, and in vitro experiments. Methods The GSE100927 and GSE28829 datasets wer...

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Bibliographic Details
Main Authors: Tiegen Huang, Chen Su, Quanli Su, Yali Nie, Zhenni Xiao, Yao Tang, Jiahao Wang, Xiaotian Luo, Yixin Tang
Format: Article
Language:English
Published: PeerJ Inc. 2024-11-01
Series:PeerJ
Subjects:
Carotid atherosclerosis
Autophagy
Immune cell infiltration
Bioinformatics analyses
Immunohistochemistry
Online Access:https://peerj.com/articles/18543.pdf
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