Proteomic analysis reveals a potential anticancer mechanism for a novel effervescent curcumin-ascorbic acid-polysaccharide-β-cyclodextrin inclusion complex towards colorectal cancer cells through modulation of ribosome biogenesis

Proteomic analysis reveals a potential anticancer mechanism for a novel effervescent curcumin-ascorbic acid-polysaccharide-β-cyclodextrin inclusion complex towards colorectal cancer cells through modulation of ribosome biogenesis

Colorectal cancer (CRC) is a major global health issue due to its aggressiveness and high mortality rates. While curcumin, the bioactive compound from turmeric (Curcuma longa L.), exhibits anticancer properties, its low water solubility limits therapeutic potential. The present study developed a nov...

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Main Authors: Atthapan Morchang, Keerakarn Somsuan, Artitaya Rongjumnong, Churat Weeraphan, Sasivimon Pramual, Theetat Ruangjaroon, Daranee Chokchaichamnankit, Wuttichai Jaidee, Phateep Hankittichai, Chanatip Pramvichai, Rawiwan Charoensup, Arunothai Wanta, Chantragan Srisomsap, Jisnuson Svasti, Siripat Aluksanasuwan
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Carbohydrate Polymer Technologies and Applications
Subjects:
Curcumin
Cyclodextrins
Colorectal cancer
Proteomics
Ribosome biogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2666893925001148
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