Acute Chest Syndrome Progressing to ARDS in a Patient of 25-Week Gestation

Acute chest syndrome is a complication of sickle cell disease and represents the highest cause of mortality in those afflicted with the disorder. Pregnancy represents an increased risk for complications of sickle cell disease in both the mother and fetus. We present a case of a 20-year-old patient w...

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Main Authors: Jefferson Chambers, Nichole Smith, Matthew Sehring, Subramanyam Chittivelu
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2018/4243569
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author Jefferson Chambers
Nichole Smith
Matthew Sehring
Subramanyam Chittivelu
author_facet Jefferson Chambers
Nichole Smith
Matthew Sehring
Subramanyam Chittivelu
author_sort Jefferson Chambers
collection DOAJ
description Acute chest syndrome is a complication of sickle cell disease and represents the highest cause of mortality in those afflicted with the disorder. Pregnancy represents an increased risk for complications of sickle cell disease in both the mother and fetus. We present a case of a 20-year-old patient with known sickle cell disease who was at 25-week gestation and developed acute chest syndrome refractory to conventional therapies and requiring emergency cesarean section. Following delivery, the patient developed acute respiratory distress syndrome (ARDS) requiring extracorporeal membrane oxygenation (ECMO). The patient and infant eventually made full recoveries. This case highlights the importance of aggressive management of ACS and careful monitoring in a pregnant patient.
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publishDate 2018-01-01
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series Case Reports in Critical Care
spelling doaj-art-e739ca00752d4b5fb1fcce96069ae8ae2025-02-03T01:21:18ZengWileyCase Reports in Critical Care2090-64202090-64392018-01-01201810.1155/2018/42435694243569Acute Chest Syndrome Progressing to ARDS in a Patient of 25-Week GestationJefferson Chambers0Nichole Smith1Matthew Sehring2Subramanyam Chittivelu3University of Illinois College of Medicine at Peoria, Peoria, IL, USAUniversity of Illinois College of Medicine at Peoria, Peoria, IL, USAUniversity of Illinois College of Medicine at Peoria, Peoria, IL, USAUniversity of Illinois College of Medicine at Peoria, Peoria, IL, USAAcute chest syndrome is a complication of sickle cell disease and represents the highest cause of mortality in those afflicted with the disorder. Pregnancy represents an increased risk for complications of sickle cell disease in both the mother and fetus. We present a case of a 20-year-old patient with known sickle cell disease who was at 25-week gestation and developed acute chest syndrome refractory to conventional therapies and requiring emergency cesarean section. Following delivery, the patient developed acute respiratory distress syndrome (ARDS) requiring extracorporeal membrane oxygenation (ECMO). The patient and infant eventually made full recoveries. This case highlights the importance of aggressive management of ACS and careful monitoring in a pregnant patient.http://dx.doi.org/10.1155/2018/4243569
spellingShingle Jefferson Chambers
Nichole Smith
Matthew Sehring
Subramanyam Chittivelu
Acute Chest Syndrome Progressing to ARDS in a Patient of 25-Week Gestation
Case Reports in Critical Care
title Acute Chest Syndrome Progressing to ARDS in a Patient of 25-Week Gestation
title_full Acute Chest Syndrome Progressing to ARDS in a Patient of 25-Week Gestation
title_fullStr Acute Chest Syndrome Progressing to ARDS in a Patient of 25-Week Gestation
title_full_unstemmed Acute Chest Syndrome Progressing to ARDS in a Patient of 25-Week Gestation
title_short Acute Chest Syndrome Progressing to ARDS in a Patient of 25-Week Gestation
title_sort acute chest syndrome progressing to ards in a patient of 25 week gestation
url http://dx.doi.org/10.1155/2018/4243569
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AT nicholesmith acutechestsyndromeprogressingtoardsinapatientof25weekgestation
AT matthewsehring acutechestsyndromeprogressingtoardsinapatientof25weekgestation
AT subramanyamchittivelu acutechestsyndromeprogressingtoardsinapatientof25weekgestation