Clinical and genetic characterization of Lenz-Majewski syndrome with a PTDSS1 variant: a case report and literature review

IntroductionLenz-Majewski syndrome (LMS) is an ultra-rare congenital disorder with progressive skeletal dysplasia, cutis laxa, and intellectual disability, typically caused by pathogenic variants in the PTDSS1 gene.MethodsOur patient with multiple malformations and developmental delay who was treate...

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Bibliographic Details
Main Authors: Yahua Zhang, You Wu, Lulu Yan, Yuxin Zhang, Haibo Li, Yan He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1617541/full
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